Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 6 November 1981:
Vol. 214. no. 4521, pp. 671 - 673
DOI: 10.1126/science.7292006
Prev | Table of Contents | Next

Articles

Science, Vol 214, Issue 4521, 671-673
Copyright © 1981 by American Association for the Advancement of Science

articles

Intraventricular calcitonin inhibits gastric acid secretion

JE Morley, AS Levine, and SE Silvis

Parenteral and intracerebroventricular administration of calcitonin in rats resulted in the suppression of gastric acid secretion. This suppression also occurred in rats with insulin-induced hypoglycemia and after the administration of thyrotropin-releasing hormone. Intracerebroventricularly administered calcitonin was 1000 times more effective than parenterally administered calcitonin in suppressing gastric acid secretion. Calcitonin also inhibited the development of stress-induced ulcers in rats.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Central Effects of Calcitonin Receptor-Stimulating Peptide-1 on Energy Homeostasis in Rats.
H. Sawada, H. Yamaguchi, T. Shimbara, K. Toshinai, M. S. Mondal, Y. Date, N. Murakami, T. Katafuchi, N. Minamino, H. Nunoi, et al. (2006)
Endocrinology 147, 2043-2050
   Abstract »    Full Text »    PDF »
Calcitonin Receptor-stimulating Peptide, a New Member of the Calcitonin Gene-related Peptide Family. ITS ISOLATION FROM PORCINE BRAIN, STRUCTURE, TISSUE DISTRIBUTION, AND BIOLOGICAL ACTIVITY.
T. Katafuchi, K. Kikumoto, K. Hamano, K. Kangawa, H. Matsuo, and N. Minamino (2003)
J. Biol. Chem. 278, 12046-12054
   Abstract »    Full Text »    PDF »
Calcium, Phosphorus, Magnesium, and Calcitonin Concentrations in the Serum and Cerebrospinal Fluid of Children.
P. S. Venkataraman, M. R. Kirk, R. C. Tsang, and I-W. Chen (1987)
Arch Pediatr Adolesc Med 141, 751-753
   Abstract »    PDF »
Prostaglandin E2: a neuromodulator in the central control of gastrointestinal motility and feeding behavior by calcitonin.
M. Fargeas, J Fioramonti, and L Bueno (1984)
Science 225, 1050-1052
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)