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Science 9 October 1981:
Vol. 214. no. 4517, pp. 190 - 193
DOI: 10.1126/science.6792709
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Articles

Science, Vol 214, Issue 4517, 190-193
Copyright © 1981 by American Association for the Advancement of Science

articles

Steady-state relationship of calcium-45 between bone and blood: differences in growing dogs, chicks, and rats

L Klein

In young animals that had received multiple doses of calcium-45, a constant ratio of calcium-45 specific activity in blood to that in bone was found in growing dogs and chicks but not in rats. This steady-state relationship of calcium-45 between bone and blood suggests that during growth in dogs and chicks most of the skeletal calcium is in an active state of turnover. In growing rats, after the first 2 weeks of life, the blood/bone ratio of calcium-45 decreases due to a decrease in bone resorption.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)