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Science 21 August 1981:
Vol. 213. no. 4510, pp. 901 - 902
DOI: 10.1126/science.6266016
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Articles

Science, Vol 213, Issue 4510, 901-902
Copyright © 1981 by American Association for the Advancement of Science

articles

Hyperkeratosis induced by sunlight degradation products of the major polybrominated biphenyl in Firemaster

DG Patterson, RH Hill, LL Needham, DL Orti, RD Kimbrough, and JA Liddle

Sunlight photodegradation of 2,2', 4,4', 5,5' -hexabromobiphenyl, the major component of Firemaster, gave a mixture that produces severe hyperkeratosis of the rabbit ear. This component in its pure state does not cause hyperkeratosis. One or more of the four major photolysis products must be responsible for this activity. A similar photodegradation pattern was observed for 2,2', 3,4,4', 5,5' -heptabromobiphenyl, the second largest component of Firemaster.




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