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Science 31 July 1981:
Vol. 213. no. 4507, pp. 553 - 555
DOI: 10.1126/science.6264606
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Articles

Science, Vol 213, Issue 4507, 553-555
Copyright © 1981 by American Association for the Advancement of Science

articles

Plasmid DNA in Treponema pallidum (Nichols): potential for antibiotic resistance by syphilis bacteria

MV Norgard and JN Miller

A plasmid DNA structure (approximate molecular weight = 7.5 X 10(6)) was identified in the human pathogen Treponema pallidum (Nichols). The inability to isolate this plasmid from rabbit host tissue and the total lack of DNA homology of the plasmid with rabbit DNA has confirmed its Treponema pallidum origin. The observation documents a newly recognized and potentially significant genetic capability for Treponema pallidum.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Treatment of Primary and Secondary Syphilis: Defining Failure at Three- and Six-Month Follow-up.
M. E. Guinan (1987)
JAMA 257, 359-360
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