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Science 17 July 1981:
Vol. 213. no. 4505, pp. 359 - 360
DOI: 10.1126/science.6113689
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Articles

Science, Vol 213, Issue 4505, 359-360
Copyright © 1981 by American Association for the Advancement of Science

articles

Bee venom enhances guanylate cyclase activity

DL Vesely

Bee venom and phospholipase A2 extracted from bee venom enhanced guanylate cyclase (E.C. 4.6.1.2) activity two- to threefold in rat liver, lung, heart, kidney, ileum, and cerebellum. Dose-response relationships revealed that bee venom at concentrations as low as 1 microgram per milliliter and phospholipase A2 at 1 microunit per milliliter caused a maximal enhancement of guanylate cyclase.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)