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Science 10 July 1981:
Vol. 213. no. 4504, pp. 238 - 239
DOI: 10.1126/science.7244633
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Articles

Science, Vol 213, Issue 4504, 238-239
Copyright © 1981 by American Association for the Advancement of Science

articles

Chloramphenicol administration during brain development: impairment of avoidance learning in adulthood

A Bertolini and R Poggioli

Rats treated with chloramphenicol from days 7 to 21 of intrauterine life (50 milligrams per kilogram per day, injected subcutaneously into the mothers) or in the first 3 days of extrauterine life (50 to 100 milligrams per kilogram per day) were trained for avoidance conditioning when 60 days old. The acquisition of the avoidance response was impaired to a highly significant degree in all the treated groups.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Birthweight Depression in Male Rats Contiguous to Male Siblings in Utero Exposed to High Doses of 1,3-Butanediol during Organogenesis.
R. F. Mankes, V. Renak, J. Fieseher, and R. Lefevre (1986)
International Journal of Toxicology 5, 189-196
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