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Science 10 July 1981:
Vol. 213. no. 4504, pp. 233 - 235
DOI: 10.1126/science.6787705
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Articles

Science, Vol 213, Issue 4504, 233-235
Copyright © 1981 by American Association for the Advancement of Science

articles

Serum albumin beads: an injectable, biodegradable system for the sustained release of drugs

TK Lee, TD Sokoloski, and GP Royer

Biologically active compounds were entrapped in cross-linked serum albumin microbeads. Injection of these drug-impregnated beads into rabbits produced no adverse immunological reactions. Sustained release (20 days) of progesterone was demonstrated in vivo.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Mechanistic Assessment of Enzyme-Induced Degradation of Albumin-Crosslinked Hydrogels.
W. S.W. Shalaby, M. Chen, and K. Park (1992)
Journal of Bioactive and Compatible Polymers 7, 257-274
   Abstract »    PDF »
Review : Polymeric Biomaterials As Enzyme and Drug Carriers* Part V: Polymeric Matrices as Drug Delivery Systems.
S. Dumitriu, M. Popa, and M. Dumitriu (1990)
Journal of Bioactive and Compatible Polymers 5, 89-127
   PDF »


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