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Science 12 June 1981:
Vol. 212. no. 4500, pp. 1266 - 1267
DOI: 10.1126/science.7015511
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Articles

Science, Vol 212, Issue 4500, 1266-1267
Copyright © 1981 by American Association for the Advancement of Science

articles

Homogeneous fluorescent immunoassay

J Briggs, VB Elings, and DF Nicoli

A fluorescent immunoassay based on the correlation of fluctuations in particle number measures the amount of tagged species bound to micrometer-sized beads and is insensitive to background fluorescence. Without separation steps, a competitive assay can resolve I nanogram of gentamicin per milliliter from a total sample volume of only 10 microliters.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Fluorescence correlation analysis of probe diffusion simplifies quantitative pathogen detection by PCR.
N. G. Walter, P. Schwille, and M. Eigen (1996)
PNAS 93, 12805-12810
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