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Science 1 May 1981:
Vol. 212. no. 4494, pp. 569 - 571
DOI: 10.1126/science.7209554
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Articles

Science, Vol 212, Issue 4494, 569-571
Copyright © 1981 by American Association for the Advancement of Science

articles

Drug discrimination learning in lead-exposed rats

H Zenick and M Goldsmith

Lead acetate (0.02 or 0.5 percent) was administered to dams throughout the lactation period with half of the litters continuing on lead after weaning. Drug thresholds for d-amphetamine were determined by using the drug-discrimination learning paradigm. All the offspring that had been exposed to lead were less sensitive to the stimulus properties of d-amphetamine irrespective of whether or not they had continued on lead after weaning.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Low Level Lead Exposure During Neonatal Development Perturbs Cognitive Function.
E. J. Massaro and T. F. Massaro (1987)
International Journal of Toxicology 6, 441-449
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