Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 3 April 1981:
Vol. 212. no. 4490, pp. 55 - 56
DOI: 10.1126/science.7209516
Prev | Table of Contents | Next

Articles

Science, Vol 212, Issue 4490, 55-56
Copyright © 1981 by American Association for the Advancement of Science

articles

A monosialoganglioside is a monoclonal antibody-defined antigen of colon carcinoma

JL Magnani, M Brockhaus, DF Smith, V Ginsburg, M Blaszczyk, KF Mitchell, Z Steplewski, and H Koprowski

The antigen of a monoclonal antibody that is specific for cells of human carcinoma of the colon is a monosialoganglioside as determined by the direct binding of antibody to thin-layer chromatograms of total lipid extracts of tissues. Binding of antibody to chromatograms is detected by autoradiography after the application of iodine-125-labeled F(ab')2 of rabbit immunoglobulin G antibodies to mouse immunoglobulins.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Intratumoral Injection of {alpha}-gal Glycolipids Induces Xenograft-Like Destruction and Conversion of Lesions into Endogenous Vaccines.
U. Galili, K. Wigglesworth, and U. M. Abdel-Motal (2007)
J. Immunol. 178, 4676-4687
   Abstract »    Full Text »    PDF »
Sialyl Lewis X-dependent Lung Colonization of B16 Melanoma Cells through a Selectin-like Endothelial Receptor Distinct from E- or P-Selectin.
J. Zhang, J. Nakayama, C. Ohyama, M. Suzuki, A. Suzuki, M. Fukuda, and M. N. Fukuda (2002)
Cancer Res. 62, 4194-4198
   Abstract »    Full Text »    PDF »
Helicobacter pylori SabA Adhesin in Persistent Infection and Chronic Inflammation.
J. Mahdavi, B. Sonden, M. Hurtig, F. O. Olfat, L. Forsberg, N. Roche, J. Angstrom, T. Larsson, S. Teneberg, K.-A. Karlsson, et al. (2002)
Science 297, 573-578
   Abstract »    Full Text »    PDF »
Development, characterisation and diagnostic application of monoclonal antibodies against Yersinia pestis fibrinolysin and coagulase.
V.A. FEODOROVA and Z.L. DEVDARIANI (2000)
J. Med. Microbiol. 49, 261-269
   Abstract »    Full Text »    PDF »
A glycolipid antigen associated with Burkitt lymphoma defined by a monoclonal antibody.
E Nudelman, R Kannagi, S Hakomori, M Parsons, M Lipinski, J Wiels, M Fellous, and T Tursz (1983)
Science 220, 509-511
   Abstract »    PDF »
Specific antigen in serum of patients with colon carcinoma.
H Koprowski, M Herlyn, Z Steplewski, and H. Sears (1981)
Science 212, 53-55
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)