Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 27 March 1981:
Vol. 211. no. 4489, pp. 1445 - 1448
DOI: 10.1126/science.6970412
Prev | Table of Contents | Next

Articles

Science, Vol 211, Issue 4489, 1445-1448
Copyright © 1981 by American Association for the Advancement of Science

articles

Metabolic mapping of the brain's response to visual stimulation: studies in humans

ME Phelps, DE Kuhl, and JC Mazziota

These studies demonstrated increasing glucose metabolic rates in the human primary (PVC) and associative (AVC) visual cortex as the complexity of visual scenes increased. The metabolic response of the AVC increased more rapidly with scene complexity than that of the PVC, indicating the greater involvement of the higher order AVC for complex visual interpretations. Increases in local metabolic activity by as much as a factor of 2 above that of control subjects with eyes closed indicate the wide range and metabolic reserve of the visual cortex.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sevoflurane 0.25 MAC Preferentially Affects Higher Order Association Areas: A Functional Magnetic Resonance Imaging Study in Volunteers.
R. Ramani, M. Qiu, and R. T. Constable (2007)
Anesth. Analg. 105, 648-655
   Abstract »    Full Text »    PDF »
Inaugural Article: Positron emission tomography provides molecular imaging of biological processes.
M. E. Phelps (2000)
PNAS 97, 9226-9233
   Abstract »    Full Text »    PDF »
Age and Stimulus Dependency of Visually Evoked Cerebral Blood Flow Responses.
G. Panczel, M. Daffertshofer, S. Ries, D. Spiegel, and M. Hennerici (1999)
Stroke 30, 619-623
   Abstract »    Full Text »    PDF »
Spatiotemporal imaging of human brain activity using functional MRI constrained magnetoencephalography data: Monte Carlo simulations.
A. K. Liu, J. W. Belliveau, and A. M. Dale (1998)
PNAS 95, 8945-8950
   Abstract »    Full Text »    PDF »
Visually Evoked Blood Flow Response Assessed by Simultaneous Two-Channel Transcranial Doppler Using Flow Velocity Averaging.
M. Sturzenegger, D. W. Newell, and R. Aaslid (1996)
Stroke 27, 2256-2261
   Abstract »    Full Text »
Visually Evoked Cerebral Blood Flow Velocity Changes in Different States of Brain Dysfunction.
V. U. Becker, H. C. Hansen, U. Brewitt, and A. Thie (1996)
Stroke 27, 446-449
   Abstract »    Full Text »
Functional mapping of the human visual cortex by magnetic resonance imaging.
J. Belliveau, D. Kennedy Jr, R. McKinstry, B. Buchbinder, R. Weisskoff, M. Cohen, J. Vevea, T. Brady, and B. Rosen (1991)
Science 254, 716-719
   Abstract »    PDF »
Brain Glucose Metabolism in Postanoxic Syndrome: Positron Emission Tomographic Study.
A. G. DeVolder, A. M. Goffinet, A. Bol, C. Michel, T. de Barsy, and C. Laterre (1990)
Arch Neurol 47, 197-204
   Abstract »    PDF »
Positron emission tomography: human brain function and biochemistry.
M. Phelps and J. Mazziotta (1985)
Science 228, 799-809
   Abstract »    PDF »
Regional Brain Glucose Metabolism in Chronic Schizophrenia: A Positron Emission Transaxial Tomographic Study.
T. Farkas, A. P. Wolf, J. Jaeger, J. D. Brodie, D. R. Christman, J. S. Fowler, R. R. MacGregor, M. J. deLeon, P. deFina, A. Goldman, et al. (1984)
Arch Gen Psychiatry 41, 293-300
   Abstract »    PDF »
The Fluorodeoxyglucose 18F Scan in Alzheimer's Disease and Multi-infarct Dementia.
D. F. Benson, D. E. Kuhl, R. A. Hawkins, M. E. Phelps, J. L. Cummings, and S. Y. Tsai (1983)
Arch Neurol 40, 711-714
   Abstract »    PDF »
Positron Computed Tomography for Studies of Myocardial and Cerebral Function.
M. E. PHELPS, H. R. SCHELBERT, and J. C. MAZZIOTTA (1983)
Ann Intern Med 98, 339-359
   Abstract »    PDF »
Cerebral Glucography With Positron Tomography: Use in Normal Subjects and in Patients With Schizophrenia.
M. S. Buchsbaum, D. H. Ingvar, R. Kessler, R. N. Waters, J. Cappelletti, D. P. van Kammen, A. C. King, J. L. Johnson, R. G. Manning, R. W. Flynn, et al. (1982)
Arch Gen Psychiatry 39, 251-259
   Abstract »    PDF »
Positron Tomography and Nuclear Magnetic Resonance Imaging.
G. L. Brownell, T. F. Budinger, P. C. Lauterbur, and P. L. MCGeer (1982)
Science 215, 619-626
   Abstract »    PDF »
Metabolic mapping of functional activity in human subjects with the [18F]fluorodeoxyglucose technique.
J. Greenberg, M Reivich, A Alavi, P Hand, A Rosenquist, W Rintelmann, A Stein, R Tusa, R Dann, D Christman, et al. (1981)
Science 212, 678-680
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)