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Science 20 March 1981:
Vol. 211. no. 4488, pp. 1294 - 1302
DOI: 10.1126/science.6163211

Articles

Science, Vol 211, Issue 4488, 1294-1302
Copyright © 1981 by American Association for the Advancement of Science


articles

Sexual differentiation of the central nervous system

NJ MacLusky and F Naftolin

Sexual differentiation of reproductive and behavior patterns is largely effected by hormones produced by the gonads. In many higher vertebrates, an integral part of this process is the induction of permanent and essentially irreversible sex differences in central nervous function, in response to gonadal hormones secreted early in development.


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Hippocampal Changes in Patients With a First Episode of Major Depression.
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M. Richards, D. Kuh, R. Hardy, and M. Wadsworth (1999)
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Regulation of Androgen Receptor Messenger Ribonucleic Acid Expression in the Developing Rat Forebrain.
M. D. McAbee and L. L. DonCarlos (1999)
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J. A. Mong, E. Glaser, and M. M. McCarthy (1999)
J. Neurosci. 19, 1464-1472
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Sex Differences in the Effects of Early Neocortical Injury on Neuronal Size Distribution of the Medial Geniculate Nucleus in the Rat Are Mediated by Perinatal Gonadal Steroids.
G. D. Rosen, A. E. Herman, and A. M. Galaburda (1999)
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Androgenic Regulation of Hypothalamic Aromatase Activity in Prepubertal and Postpubertal Male Golden Hamsters.
R. D. Romeo, J. Wade, J. E. Venier, and C. L. Sisk (1999)
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Sexual Differentiation of Aromatase Activity in the Rat Brain: Effects of Perinatal Steroid Exposure.
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Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons.
A. E. Herbison (1998)
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M. D. McAbee and L. L. DonCarlos (1998)
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Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus.
S. X. Simonian, H. E. Murray, G. E. Gillies, and A. E. Herbison (1998)
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Hormonal Interactions in the Effects of Halogenated Aromatic Hydrocarbons On the Developing Brain.
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Identification of Estrogen-Responsive Genes in Neuroblastoma SK-ER3 Cells.
M. Garnier, D. Di Lorenzo, A. Albertini, and A. Maggi (1997)
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Reproductive toxicity and toxicokinetics of lindane in the male offspring of rats exposed during lactation.
P. Dalsenter, A. Faqi, J. Webb, H-J. Merker, and I. Chahoud (1997)
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Prenatal Androgens Time Neuroendocrine Puberty in the Sheep: Effect of Testosterone Dose.
S. S. Kosut, R. I. Wood, C. Herbosa-Encarnacion, and D. L. Foster (1997)
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Sexual Differentiation in the Neonate: Rodent vs. Primate Comparisons.
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Quantitative Analysis of Cerebral Asymmetries: Fronto-occipital Correlation, Sexual Dimorphism and Association With Handedness.
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N. Geschwind and A. M. Galaburda (1985)
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Functional Lateralization of the Brain.
R. S. Dean (1984)
Journal of Special Education 18, 239-256
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High fetal estrogen concentrations: correlation with increased adult sexual activity and decreased aggression in male mice.
F. vom Saal, W. Grant, C. McMullen, and K. Laves (1983)
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Effects of Androgens on the Activity of Steroid-metabolizing Enzymes in the Murine Submaxillary Gland.
H. Katsukawa, Y. Tanabe, and M. Funakoshi (1983)
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Sex differences in dendritic structure in the preoptic area of the juvenile macaque monkey brain.
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Science 219, 197-198
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