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Science 27 February 1981: Vol. 211. no. 4485, pp. 957 - 959 DOI: 10.1126/science.7466371
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Articles
Science, Vol 211, Issue 4485, 957-959
Copyright © 1981 by American Association for the Advancement of Science
Prenatal exposure to ethanol alters the organization of hippocampal mossy fibers in rats
West JR,
CA Hodges,
and
AC Black Jr
Rats exposed to ethanol throughout their gestation were found to have abnormally distributed mossy fibers in temporal regions of the hippocampus. This demonstrates that prenatal exposure to ethanol causes alterations in neuronal circuitry that persist to maturity. Such defects may play a role in the mental retardation often observed in children with fetal alcohol syndrome.
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