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Science 16 January 1981:
Vol. 211. no. 4479, pp. 291 - 294
DOI: 10.1126/science.7444468
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Articles

Science, Vol 211, Issue 4479, 291-294
Copyright © 1981 by American Association for the Advancement of Science

articles

Hydra mesoglea: a model for investigating epithelial cell--basement membrane interactions

RM Day and HM Lenhoff

Isolated hydra mesoglea served as a suitable substrate for the attachment and spreading of hydra cells in vitro, irrespective of the species tested. Hydra cells did not attach and spread on substrates typically used for culturing mammalian cells. Mammalian and Drosophila cells attached and spread on plastic culture dishes but not on isolated mesoglea. Xenopus epithelial cells spread on both plastic and mesoglea. Because of the similarities of hydra mesoglea to vertebrate basement membranes, suggestions are offered for using mesoglea to study the interactions of epithelial cells with their basement membranes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Molecular, biochemical and functional analysis of a novel and developmentally important fibrillar collagen (Hcol-I) in hydra.
R Deutzmann, S Fowler, X Zhang, K Boone, S Dexter, R. Boot-Handford, R Rachel, and M. Sarras (2000)
Development 127, 4669-4680
   Abstract »    PDF »
Cell-extracellular matrix interactions under in vivo conditions during interstitial cell migration in Hydra vulgaris.
X Zhang and M. Sarras (1994)
Development 120, 425-432
   Abstract »    PDF »
Characterization of Hydra Type IV Collagen. TYPE IV COLLAGEN IS ESSENTIAL FOR HEAD REGENERATION AND ITS EXPRESSION IS UP-REGULATED UPON EXPOSURE TO GLUCOSE.
S. J. Fowler, S. Jose, X. Zhang, R. Deutzmann, M. P. Sarras Jr., and R. P. Boot-Handford (2000)
J. Biol. Chem. 275, 39589-39599
   Abstract »    Full Text »    PDF »


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