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Science 19 December 1980:
Vol. 210. no. 4476, pp. 1367 - 1369
DOI: 10.1126/science.7434031
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Articles

Science, Vol 210, Issue 4476, 1367-1369
Copyright © 1980 by American Association for the Advancement of Science

articles

Functional development of grafted vasopressin neurons

D Gash, JR Sladek Jr, and CD Sladek

Vasopressin neurons, transplanted from normal rat fetuses into the third ventricle of adult Brattleboro rats, alleviate the polydipsia and polyuria of the hosts. Determination of the antidiuretic activity of grafted neurons in hosts with congenital diabetes insipidus provides a convenient model for analyzing the development, plasticity, and function of transplanted central nervous system neurons in mammals.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Fetal research.
J. Hansen and J. Sladek Jr (1989)
Science 246, 775-779
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Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys.
D. Redmond Jr, F Naftolin, T. Collier, C Leranth, R. Robbins, C. Sladek, R. Roth, and J. Sladek Jr (1988)
Science 242, 768-771
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Neural transplantation: a call for patience rather than patients.
J. Sladek Jr and I Shoulson (1988)
Science 240, 1386-1388
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Neocortical transplants in the mammalian brain lack a blood-brain barrier to macromolecules.
J. Rosenstein (1987)
Science 235, 772-774
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Amitotic neuroblastoma cells used for neural implants in monkeys.
D. Gash, M. Notter, S. Okawara, A. Kraus, and R. Joynt (1986)
Science 233, 1420-1422
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Promoting functional plasticity in the damaged nervous system.
W. Freed, L de Medinaceli, and R. Wyatt (1985)
Science 227, 1544-1552
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Facilitated sexual behavior reversed and serotonin restored by raphe nuclei transplanted into denervated hypothalamus.
V. Luine, K. Renner, M Frankfurt, and E. Azmitia (1984)
Science 226, 1436-1439
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Cell biology of synaptic plasticity.
C. Cotman and M Nieto-Sampedro (1984)
Science 225, 1287-1294
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Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra.
W. Freed, G. Ko, D. Niehoff, M. Kuhar, B. Hoffer, L Olson, H. Cannon-Spoor, J. Morihisa, and R. Wyatt (1983)
Science 222, 937-939
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Circumventing the blood-brain barrier with autonomic ganglion transplants.
J. Rosenstein and M. Brightman (1983)
Science 221, 879-881
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Enhancement of sexual behavior in female rats by neonatal transplantation of brain tissue from males.
G. Arendash and R. Gorski (1982)
Science 217, 1276-1278
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