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Science 21 November 1980:
Vol. 210. no. 4472, pp. 901 - 903
DOI: 10.1126/science.7001630
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Articles

Science, Vol 210, Issue 4472, 901-903
Copyright © 1980 by American Association for the Advancement of Science

articles

Cellular transplantation in the treatment of experimental hepatic failure

L Makowka, RE Falk, LE Rotstein, JA Falk, N Nossal, B Langer, LM Blendis, and MJ Phillips

The survival of Lewis rats with D-galactosamine-induced fulminant hepatic failure was prolonged if they were given intraperitoneal injections of single-cell suspensions of liver or bone marrow cells from normal rats. Suspensions of liver cells were also effective in prolonging the survival of rats with ischemia-induced hepatic necrosis. The liver cells did not act by repopulating the recipient liver.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)