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Science 31 October 1980:
Vol. 210. no. 4469, pp. 550 - 551
DOI: 10.1126/science.7423205
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Articles

Science, Vol 210, Issue 4469, 550-551
Copyright © 1980 by American Association for the Advancement of Science

articles

Neuronal control of acetylcholine receptor turnover rate at a vertebrate neuromuscular junction

TA Levitt, RH Loring, and MM Salpeter

The turnover rate of acetylcholine receptors at neuromuscular junctions in mice increases progressively after denervation and, after 15 days, reaches a half-time of 30 z 5 hours. Denervation thus causes the clustered junctional acetylcholine receptors to assume the rapid turnover characteristic of extrajunctional receptors before innervation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Regulation of the Intermediate Filament Protein Nestin at Rodent Neuromuscular Junctions by Innervation and Activity.
H. Kang, L. Tian, Y.-J. Son, Y. Zuo, D. Procaccino, F. Love, C. Hayworth, J. Trachtenberg, M. Mikesh, L. Sutton, et al. (2007)
J. Neurosci. 27, 5948-5957
   Abstract »    Full Text »    PDF »
The Ets Transcription Factor GABP Is Required for Postsynaptic Differentiation In Vivo.
A. Briguet and M. A. Ruegg (2000)
J. Neurosci. 20, 5989-5996
   Abstract »    Full Text »    PDF »
Rapid and Reversible Effects of Activity on Acetylcholine Receptor Density at the Neuromuscular Junction in Vivo.
M. Akaaboune, S. M. Culican, S. G. Turney, and J. W. Lichtman (1999)
Science 286, 503-507
   Abstract »    Full Text »


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