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Science 17 October 1980:
Vol. 210. no. 4467, pp. 330 - 332
DOI: 10.1126/science.7423194
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Articles

Science, Vol 210, Issue 4467, 330-332
Copyright © 1980 by American Association for the Advancement of Science

articles

Genetic mosaics of Caenorhabditis elegans: a tissue-specific fluorescent mutant

SS Siddiqui and P Babu

Genetic mosaics can be generated by x-irradiation in the simple nematode Caenorhabditis elegans. A mutation in the gene flu-3 alters the characteristic autofluorescence of intestinal cells under ultraviolet light and can be used as a cell- and tissue-specific marker. Embryos heterozygous for flu-3 give rise to adults with patches of these altered intestinal cells. The previously established intestinal cell lineage in Caenorhabditis elegans and the distribution and sizes of the fluorescent patches are consistent with a somatic segregation of the flu-3 allele.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Establishment of gut fate in the E lineage of C. elegans: the roles of lineage-dependent mechanisms and cell interactions.
B Goldstein (1993)
Development 118, 1267-1277
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