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Science 26 September 1980:
Vol. 209. no. 4464, pp. 1547 - 1548
DOI: 10.1126/science.7433978
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Articles

Science, Vol 209, Issue 4464, 1547-1548
Copyright © 1980 by American Association for the Advancement of Science

articles

Anxiety and muscle tension as consequences of caffeine withdrawal

BC White, CA Lincoln, NW Pearce, R Reeb, and C Vaida

Regular consumers of caffeine had higher muscle tension after three or more hours of abstinence than low caffeine consumers. This difference was absent after double-blind administration of caffeine citrate or placebo. In a discriminative reaction time test, caffeine treatment improved performance. Among subjects receiving placebo, anxiety was highly correlated with prior caffeine use, suggesting that even a brief abstinence may produce anxiety in the regular user.


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Caffeine as an Analgesic Adjuvant.
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The Health Consequences of Caffeine.
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