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Science 15 August 1980:
Vol. 209. no. 4458, pp. 825 - 827
DOI: 10.1126/science.7406957
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Articles

Science, Vol 209, Issue 4458, 825-827
Copyright © 1980 by American Association for the Advancement of Science

articles

Factors influencing the inhibitory effect of selenium on mice inoculated with Ehrlich ascites tumor cells

GA Greeder and JA Milner

Selenium, administered to mice with Ehrlich ascites tumors, effectively limited tumor growth. The response was dependent on the chemical form and dose of selenium administered. At the doses administered, there were no detectable adverse effects to the host.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Locally Generated Methylseleninic Acid Induces Specific Inactivation of Protein Kinase C Isoenzymes: RELEVANCE TO SELENIUM-INDUCED APOPTOSIS IN PROSTATE CANCER CELLS.
U. Gundimeda, J. E. Schiffman, D. Chhabra, J. Wong, A. Wu, and R. Gopalakrishna (2008)
J. Biol. Chem. 283, 34519-34531
   Abstract »    Full Text »    PDF »
Selenium disrupts estrogen receptor {alpha} signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells.
Y. M. Shah, M. Al-Dhaheri, Y. Dong, C. Ip, F. E. Jones, and B. G. Rowan (2005)
Mol. Cancer Ther. 4, 1239-1249
   Abstract »    Full Text »    PDF »
Selective Modulation of the Therapeutic Efficacy of Anticancer Drugs by Selenium Containing Compounds against Human Tumor Xenografts.
S. Cao, F. A. Durrani, and Y. M. Rustum (2004)
Clin. Cancer Res. 10, 2561-2569
   Abstract »    Full Text »    PDF »
Selenium Attenuates Lipopolysaccharide-Induced Oxidative Stress Responses Through Modulation of p38 MAPK and NF-{kappa}B Signaling Pathways.
S. H. Kim, V. J. Johnson, T.-Y. Shin, and R. P. Sharma (2004)
Experimental Biology and Medicine 229, 203-213
   Abstract »    Full Text »    PDF »
Antioxidant Regulation of Protein Kinase C in Cancer Prevention.
R. Gopalakrishna and U. Gundimeda (2002)
J. Nutr. 132, 3819S-3823
   Abstract »    Full Text »    PDF »
Selenium Supplementation and Lung Cancer Incidence: An Update of the Nutritional Prevention of Cancer Trial.
M. E. Reid, A. J. Duffield-Lillico, L. Garland, B. W. Turnbull, L. C. Clark, and J. R. Marshall (2002)
Cancer Epidemiol. Biomarkers Prev. 11, 1285-1291
   Abstract »    Full Text »    PDF »
Selenite Negatively Regulates Caspase-3 through a Redox Mechanism.
H.-S. Park, S.-H. Huh, Y. Kim, J. Shim, S.-H. Lee, I.-S. Park, Y.-K. Jung, I. Y. Kim, and E.-J. Choi (2000)
J. Biol. Chem. 275, 8487-8491
   Abstract »    Full Text »    PDF »
Selenite Inhibits the c-Jun N-terminal Kinase/Stress-activated Protein Kinase (JNK/SAPK) through a Thiol Redox Mechanism.
H.-S. Park, E. Park, M.-S. Kim, K. Ahn, I. Y. Kim, and E.-J. Choi (2000)
J. Biol. Chem. 275, 2527-2531
   Abstract »    Full Text »    PDF »
The Chemopreventive Role of Selenium in Carcinogenesis.
C. Ip (1986)
International Journal of Toxicology 5, 7-20
   PDF »
Mechanisms of Selenium Inhibition of Tumorigenesis.
D. Medina (1986)
International Journal of Toxicology 5, 21-27
   PDF »
The Role of Selenium Compounds in Cancer Therapy.
G. Batist, A.G. Katki, V.J. Ferrans, and C.E. Myers (1986)
International Journal of Toxicology 5, 87-93
   Abstract »    PDF »


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