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Science 8 August 1980:
Vol. 209. no. 4457, pp. 703 - 704
DOI: 10.1126/science.7394528
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Articles

Science, Vol 209, Issue 4457, 703-704
Copyright © 1980 by American Association for the Advancement of Science

articles

C-Glucuronidation of the acetylenic moiety of ethchlorvynol in the rabbit

CR Abolin, TN Tozer, JC Craig, and LD Gruenke

An acetylenic C-glucuronide of the sedative-hypnotic drug ethchlorvynol was isolated from rabbit urine as the major metabolite. The C-glucuronide represents a novel metabolic pathway for acetylenes and is a rare example of the formation of a carbon-glucuronide bond in mammalian systems.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)