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Science 11 July 1980:
Vol. 209. no. 4453, pp. 287 - 289
DOI: 10.1126/science.6155699

Articles

Science, Vol 209, Issue 4453, 287-289
Copyright © 1980 by American Association for the Advancement of Science


articles

Mammoth albumin

EM Prager, AC Wilson, JM Lowenstein, and VM Sarich

Serum albumin was detected immunologically in muscle from a mammoth that died about 40,000 years ago. Rabbits injected with ground mammoth muscle produced antibodies that react strongly with elephant albumin, weakly with sea cow albumin, and still more weakly or not at all with other mammalian albumins. Since elephant albumin elicited antibodies with the same specificity, some of the surviving mammoth albumin molecules evidently have antigenic sites identical to those on native elephant albumin. Much of the mammoth albumin has, however, undergone postmortem change. The small amount of soluble albumin extractable from mammoth muscle is heterogeneous in size, charge, and antigenic properties.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prehistoric Blood Residues: Detection on Tool Surfaces and Identification of Species of Origin.
T. H. Loy and T. H. LOY (1983)
Science 220, 1269-1271
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