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Science 27 June 1980:
Vol. 208. no. 4451, pp. 1475 - 1476
DOI: 10.1126/science.7384790
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Articles

Science, Vol 208, Issue 4451, 1475-1476
Copyright © 1980 by American Association for the Advancement of Science

articles

Social environment as a factor in diet-induced atherosclerosis

RM Nerem, MJ Levesque, and JF Cornhill

Rabbits on a 2 percent cholesterol diet were individually petted, held, talked to, and played with on a regular basis. Measurements of aortic affinity for a Sudan stain, serum cholesterol levels, heart rate, and blood pressure were made at the end of the experimental period. Compared to control groups, which were given the same diet and normal laboratory animal care, the experimental groups showed more than a 60 percent reduction in the percentage of aortic surface area exhibiting sudanophilic lesions, even though serum cholesterol levels, heart rate, and blood pressure were comparable.


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J Neurophysiol 81, 2753-2763
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Emotional Support and Survival after Myocardial Infarction: A Prospective, Population-based Study of the Elderly.
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Social relationships and health.
J. House, K. Landis, and D Umberson (1988)
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Social stress and atherosclerosis in normocholesterolemic monkeys.
Kaplan JR, S. Manuck, T. Clarkson, F. Lusso, D. Taub, and E. Miller (1983)
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Effects of Stress Management Training and Dietary Changes in Treating Ischemic Heart Disease.
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