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Science 25 April 1980:
Vol. 208. no. 4442, pp. 419 - 421
DOI: 10.1126/science.7367871
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Articles

Science, Vol 208, Issue 4442, 419-421
Copyright © 1980 by American Association for the Advancement of Science

articles

Interspecific chimeras in mammals: successful production of live chimeras between Mus musculus and Mus caroli

J Rossant and WI Frels

Live chimeras between two species of mouse, Mus musculus and Mus caroli, were produced by blastocyst injection. These chimeras were entirely similar to M. musculus in equilibrium with M. musculus chimeras in their somatic tissue organization. This is the first report of completely normal development of interspecific chimeras in mammals.


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