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Science 25 April 1980:
Vol. 208. no. 4442, pp. 408 - 410
DOI: 10.1126/science.7367868
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Articles

Science, Vol 208, Issue 4442, 408-410
Copyright © 1980 by American Association for the Advancement of Science

articles

Survival of mice receiving melanoma transplants is promoted by hydroquinone

W Chavin, EJ Jelonek Jr, AH Reed, and LR Binder

In BALB/c female mice with melanoma transplants, the incidence of "takes" is decreased and survival is increased by hydroquinone, a melanocytolytic agent. The mechanism of drug action is suggested by via DNA. The significant and high degree of positive response to hydroquinone treatment in vivo is encouraging for the clinical management of melanoma with melanocytolytic agents.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
4: Final Report on the Safety Assessment of Hydroquinone and Pyrocatechol.
(1986)
International Journal of Toxicology 5, 123-165
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