Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 18 April 1980:
Vol. 208. no. 4441, pp. 291 - 293
DOI: 10.1126/science.6245445
Prev | Table of Contents | Next

Articles

Science, Vol 208, Issue 4441, 291-293
Copyright © 1980 by American Association for the Advancement of Science

articles

Glutamine- and N-acetylglutamate-dependent carbamoyl phosphate synthetase in elasmobranchs

PM Anderson

High levels of glutamine- and N-acetyl-L-glutamate-dependent carbamoyl phosphate synthetase activity are present in liver extracts of marine species of fish that retain high levels of urea in their tissues for the purpose of osmoregulation. The function of the synthetase in these species appears to be related to urea synthesis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The freshwater Amazonian stingray, Potamotrygon motoro, up-regulates glutamine synthetase activity and protein abundance, and accumulates glutamine when exposed to brackish (15{per thousand}) water.
Y. K. Ip, A. M. Loong, B. Ching, G. H. Y. Tham, W. P. Wong, and S. F. Chew (2009)
J. Exp. Biol. 212, 3828-3836
   Abstract »    Full Text »    PDF »
The accumulation of methylamine counteracting solutes in elasmobranchs with differing levels of urea: a comparison of marine and freshwater species.
J. R. Treberg, B. Speers-Roesch, P. M. Piermarini, Y. K. Ip, J. S. Ballantyne, and W. R. Driedzic (2006)
J. Exp. Biol. 209, 860-870
   Abstract »    Full Text »    PDF »
Urea synthesis in the African lungfish Protopterus dolloi - hepatic carbamoyl phosphate synthetase III and glutamine synthetase are upregulated by 6 days of aerial exposure.
S. F. Chew, T. F. Ong, L. Ho, W. L. Tam, A. M. Loong, K. C. Hiong, W. P. Wong, and Y. K. Ip (2003)
J. Exp. Biol. 206, 3615-3624
   Abstract »    Full Text »    PDF »
A comparison of the effects of environmental ammonia exposure on the Asian freshwater stingray Himantura signifer and the Amazonian freshwater stingray Potamotrygon motoro.
Y. K. Ip, W. L. Tam, W. P. Wong, A. M. Loong, K. C. Hiong, J. S. Ballantyne, and S. F. Chew (2003)
J. Exp. Biol. 206, 3625-3633
   Abstract »    Full Text »    PDF »
The osmotic response of the Asian freshwater stingray (Himantura signifer) to increased salinity: a comparison with marine (Taeniura lymma) and Amazonian freshwater (Potamotrygon motoro) stingrays.
W. L. Tam, W. P. Wong, A. M. Loong, K. C. Hiong, S. F. Chew, J. S. Ballantyne, and Y. K. Ip (2003)
J. Exp. Biol. 206, 2931-2940
   Abstract »    Full Text »    PDF »
Expression of Carbamoyl-phosphate Synthetase III mRNA during the Early Stages of Development and in Muscle of Adult Rainbow Trout (Oncorhynchus mykiss).
J. J. Korte, W. L. Salo, V. M. Cabrera, P. A. Wright, A. K. Felskie, and P. M. Anderson (1997)
J. Biol. Chem. 272, 6270-6277
   Abstract »    Full Text »    PDF »
Nucleotide Sequence and Tissue-specific Expression of the Multifunctional Protein Carbamoyl-phosphate Synthetase-Aspartate Transcarbamoylase-Dihydroorotase (CAD) mRNA in Squalus acanthias.
J. Hong, W. L. Salo, and P. M. Anderson (1995)
J. Biol. Chem. 270, 14130-14139
   Abstract »    Full Text »    PDF »
Evolution of urea synthesis in vertebrates: the piscine connection.
T. Mommsen and P. Walsh (1989)
Science 243, 72-75
   Abstract »    PDF »
Glutamine synthetase: assimilatory role in liver as related to urea retention in marine chondrichthyes.
J. Webb and G. Brown Jr (1980)
Science 208, 293-295
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)