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Science 14 March 1980:
Vol. 207. no. 4436, pp. 1220 - 1222
DOI: 10.1126/science.7355285
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Articles

Science, Vol 207, Issue 4436, 1220-1222
Copyright © 1980 by American Association for the Advancement of Science

articles

Mebendazole therapy of parenteral trichinellosis

RO McCracken and DD Taylor

Mebendazole was highly effective against the helminth parasite Trichinella spiralis in mice subjected to a 3-day course of treatment during the invasive and encystment phases of experimental trichinellosis. When treatment began either 2 or 4 weeks after the mice were inoculated with parasites, the number of larvae developing in the host musculature was greatly reduced by twice-daily oral administration of 3.125, 6.25, or 12.5 milligrams of mebendazole per kilogram of body weight.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Topical Review: Parasitic Infections of the Central Nervous System in Children. Part II: Disseminated Infections.
A. Lowichik and A. J. Ruff (1995)
J Child Neurol 10, 77-87
   Abstract »    PDF »
Persistent Strongyloides stercoralis in a Blind Loop of the Bowel: Successful Treatment With Mebendazole.
K. H. Wilson and C. A. Kauffman (1983)
Arch Intern Med 143, 357-358
   Abstract »    PDF »


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