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Science 8 February 1980:
Vol. 207. no. 4431, pp. 651 - 653
DOI: 10.1126/science.7352277
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Articles

Science, Vol 207, Issue 4431, 651-653
Copyright © 1980 by American Association for the Advancement of Science

articles

Angiotoxicity of oxygenated sterols and possible precursors

H Imai, NT Werthessen, V Subramanyam, PW LeQuesne, AH Soloway, and M Kanisawa

Cell death, inflammation, and repair in rabbits' aortas and pulmonary arteries were observed at 3-, 7-, and 10-day periods after the intravenous injection of oxygenated sterols. Thus, oxygenated sterols, not cholesterol, may play the primary role in arterial wall injury and lesion development.


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