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Science 1 February 1980:
Vol. 207. no. 4430, pp. 525 - 526
DOI: 10.1126/science.7352259
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Articles

Science, Vol 207, Issue 4430, 525-526
Copyright © 1980 by American Association for the Advancement of Science

articles

Human fibroblast interferon: amino acid analysis and amino terminal amino acid sequence

E Knight Jr, MW Hunkapiller, BD Korant, RW Hardy, and LE Hood

The purification of human fibroblast interferon has been simplified to a two-step procedure consisting of affinity chromatography on Blue Sepharose and sodium dodecyl sulfate polyacrlamide gel electrophoresis. A preliminary amino acid composition and the sequence of the 13 amino-terminal residues of homogeneous interferon prepared by this method is reported.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Y. Yip, B. Barrowclough, C Urban, and J Vilcek (1982)
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At least three human type alpha interferons: structure of alpha 2.
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Frontiers in Chemistry.
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New protein sequenator with increased sensitivity.
M. Hunkapiller and L. Hood (1980)
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Amino terminal sequence of the major component of human lymphoblastoid interferon.
K. Zoon, M. Smith, P. Bridgen, C. Anfinsen, M. Hunkapiller, and L. Hood (1980)
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Mouse interferons: amino terminal amino acid sequences of various species.
H Taira, R. Broeze, B. Jayaram, P Lengyel, M. Hunkapiller, and L. Hood (1980)
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