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Science 18 January 1980:
Vol. 207. no. 4428, pp. 307 - 308
DOI: 10.1126/science.6444254
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Articles

Science, Vol 207, Issue 4428, 307-308
Copyright © 1980 by American Association for the Advancement of Science

articles

Myosin heads do not move on activation in highly stretched vertebrate striated muscle

N Yagi and I Matsubara

Highly stretched muscles in which thick and thin filaments no longer overlap produce little or no tension on activation. In preparations producing no tension, the 42.9-nanometer myosin layer line shown in x-ray diffraction patterns does not become weaker. This suggests that myosin heads do not move from their resting positions in the absence of actin.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)