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Science 21 December 1979:
Vol. 206. no. 4425, pp. 1419 - 1421
DOI: 10.1126/science.92053

Articles

Science, Vol 206, Issue 4425, 1419-1421
Copyright © 1979 by American Association for the Advancement of Science


articles

Visualization of polymercurimethane-labeled for bacteriophage in the scanning transmission electron microscope

JJ Lipka, SJ Lippard, and JS Wall

Each of the 2700 coat proteins of fd bacteriophage was labeled with tetrakis(acetoxymercuri)methane (TAMM) or aquoglycylmethionineplatinum(II). The TAMM-labeled specimens reveal striking bright spots in the scanning transmission electron microscope which arise from clustering. Measurements of mass show increases consistent with the addition of four mercury atoms or one platinum atom, respectively, to each coat protein.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Studies of Nucleosome Structure.
T.J. Richmond, J.T. Finch, and A. Klug (1983)
Cold Spring Harb Symp Quant Biol 47, 493-501
   Abstract »    PDF »
Biospecific labeling with undecagold: visualization of the biotin-binding site on avidin.
D Safer, J Hainfeld, J. Wall, and J. Reardon (1982)
Science 218, 290-291
   Abstract »    PDF »



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