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Science 9 November 1979:
Vol. 206. no. 4419, pp. 693 - 695
DOI: 10.1126/science.493974
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Articles

Science, Vol 206, Issue 4419, 693-695
Copyright © 1979 by American Association for the Advancement of Science

articles

Xenopus liver: ontogeny of estrogen responsiveness

JK Skipper and TH Hamilton

Estradiol-17 beta stimulates the synthesis of numerous proteins exported into the culture medium by Xenopus tadpole liver tissue obtained after stage 50 and throughout metamorphosis to stage 66. Although estrogen-induced vitellogenin can be detected as early as stage 54, it is a minor percentage of the exported proteins until after the completion of metamorphosis. In hepatic tissue obtained after metamorphosis, the hormone evokes the synthesis of vitellogenin specifically without affecting the labeling of other secreted proteins.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Vitellogenesis and the vitellogenin gene family.
W Wahli, I. Dawid, G. Ryffel, and R Weber (1981)
Science 212, 298-304
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