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Science 5 October 1979:
Vol. 206. no. 4414, pp. 71 - 72
DOI: 10.1126/science.39339
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Articles

Science, Vol 206, Issue 4414, 71-72
Copyright © 1979 by American Association for the Advancement of Science

articles

Tyrosine hydroxylase immunoreactivity in familial dysautonomia

J Pearson, L Brandeis, and M Goldstein

Tyrosine hydroxylase antigen was localized immunohistochemically in sympathetic neurons from human autopsy tissue. The reaction persists in paraffin-embedded tissue, and the method is applicable to archival specimens. Increased amounts in this antigen per cell may partially compensate for decreased numbers of sympathetic neurons in familial dysautonomia.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)