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Science 28 September 1979:
Vol. 205. no. 4413, pp. 1397 - 1399
DOI: 10.1126/science.472755
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Articles
Science, Vol 205, Issue 4413, 1397-1399
Copyright © 1979 by American Association for the Advancement of Science
Meiotic maturation in Xenopus laevis oocytes initiated by insulin
M El-Etr,
S Schorderet-Slatkine,
and
EE Baulieu
Insulin can induce meiotic division in Xenopus laevis oocytes. This effect shows the specificity expected of a receptor-mediated mechanism. It is potentiated by ethynylestradiol, a steroid antagonist of pregesterone (the natural hormone that provokes meiosis). The Xenopus laevis oocytes may serve as a model for the study of the poorly understood effect of insulin on cell division.
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