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Science 3 August 1979: Vol. 205. no. 4405, pp. 513 - 515 DOI: 10.1126/science.109924
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Articles
Science, Vol 205, Issue 4405, 513-515
Copyright © 1979 by American Association for the Advancement of Science
Stress and coping factors influence tumor growth
LS Sklar
and
H Anisman
Growth of syngeneic P815 mastocytoma in DBA/2J male mice was evaluated as a result of various stress regimens. A single session of inescapable shock resulted in earlier tumor appearance, exaggeration of tumor size, and decreased survival time in recipient animals. Escapable shock had no such effects. The effects of the inescapable shock were mitigated if mice received long-term shock treatment.
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