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Science 3 August 1979:
Vol. 205. no. 4405, pp. 507 - 508
DOI: 10.1126/science.205.4405.507

Articles

Prevention of Fungal Infection of Plants by Specific Inhibition of Cutinase

I. B. MAITI 1 and P. E. KOLATTUKUDY 1

1 Department of Agricultural Chemistry and Program in Biochemistry and Biophysics, Washington State University, Pullman 99164

Specific antibodies prepared against cutinase from Fusarium solani pisi and diisopropylfluorophosphate, a potent inhibitor of this enzyme, prevented infection of the host (pea epicotyl) by this organism, without affecting the viability of the spores. This finding shows that enzymatic penetration of cuticle is involved in pathogenesis.

Submitted on January 26, 1979
Revised on April 27, 1979


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