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Science 22 June 1979:
Vol. 204. no. 4399, pp. 1308 - 1309
DOI: 10.1126/science.451536
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Articles

Science, Vol 204, Issue 4399, 1308-1309
Copyright © 1979 by American Association for the Advancement of Science

articles

Antibody-selective membrane electrodes

RL Solsky and GA Rechnitz

Direct antibody-sensing membrane electrodes have been developed by immobilizing ion-carrier immunogen conjugates in a liquid membrane matrix. The resulting potentiometric probes measure specific antibodies with high selectivity over nonspecific antibodies in the physiological pH range. The electrode response is shown to arise from the selective interaction of the antibody with the membrane-bound immunogen.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)