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Science 25 May 1979:
Vol. 204. no. 4395, pp. 851 - 853
DOI: 10.1126/science.220708
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Articles

Science, Vol 204, Issue 4395, 851-853
Copyright © 1979 by American Association for the Advancement of Science

articles

Prolactin receptors in Rana catesbeiana during development and metamorphosis

BA White and CS Nicoll

Specific binding of ovine prolactin was found in microsomal preparations of tail, gill, and kidney of the bullfrog Ran catesbeiana. Binding by larval and adult liver and by kidney before larval stage XVII was low or nondetectable. Renal binding increased during metamorphic climax and in response to treatment with thyroid hormone. The emergence of renal binding of prolactin may signify a shift in the hormone's participation in the control of hydromineral homeostasis from the gill, which is resorbed, to the kidney. A renal action of prolactin during climax may facilitate metamorphosis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Somatomedin C: restoration in vivo of cycle traverse in G0/G1 blocked cells of hypophysectomized animals.
H Rothstein, J. Van Wyk, J. Hayden, Gordon SR, and A Weinsieder (1980)
Science 208, 410-412
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