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Science 13 April 1979:
Vol. 204. no. 4389, pp. 183 - 184
DOI: 10.1126/science.432640
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Articles

Science, Vol 204, Issue 4389, 183-184
Copyright © 1979 by American Association for the Advancement of Science

articles

Melatonin synthesis by the retina

WA Gern and CL Ralph

Melatonin fulfills many of the criteria for classification as a hormone. Until recently it was considered to be elaborated exclusively by pineal organs. Melatonin synthesis by other tissues has been indicated but not demonstrated unequivocally. Trout retinas in a whole-organ culture system in vitro synthesized tritiated melatonin from a substrate containing tritiated serotonin. This raises the possibility that the trout retina is an endocrine organ.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Effects of Moonlight Exposure on Plasma Melatonin Rhythms in the Seagrass Rabbitfish, Siganus Canaliculatus.
Md. S. Rahman, B.-H. Kim, A. Takemura, C.-B. Park, and Y.-D. Lee (2004)
J Biol Rhythms 19, 325-334
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Retinal Melatonin Production: Role of Proteasomal Proteolysis in Circadian and Photic Control of Arylalkylamine N-Acetyltransferase.
P. M. Iuvone, A. D. Brown, R. Haque, J. Weller, J. B. Zawilska, S. S. Chaurasia, M. Ma, and D. C. Klein (2002)
Invest. Ophthalmol. Vis. Sci. 43, 564-572
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Ocular Melatonin Rhythms in the Goldfish, Carassius auratus.
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J Biol Rhythms 12, 182-192
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The Visual Input Stage of the Mammalian Circadian Pacemaking System: I. Is There a Clock in the Mammalian Eye?.
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The effects of direct-current magnetic fields on turtle retinas in vitro.
M. Raybourn (1983)
Science 220, 715-717
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Methoxyindoles and photoreceptor metabolism: activation of rod shedding.
J. Besharse and D. Dunis (1983)
Science 219, 1341-1343
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Ocular and Testicular Abnormalities in Alopecia Areata.
A. C. Brown, Z. F. Pollard, and W. H. Jarrett II (1982)
Arch Dermatol 118, 546-554
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