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Science 23 March 1979:
Vol. 203. no. 4386, pp. 1245 - 1247
DOI: 10.1126/science.424750
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Articles

Science, Vol 203, Issue 4386, 1245-1247
Copyright © 1979 by American Association for the Advancement of Science

articles

Circadian rhythm of serotonin N-acetyltransferase activity in organ culture of chicken pineal gland

T Deguchi

When chicken pineal glands were organ-cultured in darkness, serotonin N-acetyltransferase activity was low during daytime, increased at midnight, and decreased on the next morning. The autonomous increase of N-acetyltransferase activity was suppressed by illumination of the glands. When pineal glands were cultured under a light-dark cycle (LD 12:12), the change of N-acetyltransferase activity continued to oscillate in phase with the light-dark cycle for 3 days.


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