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Science 16 March 1979:
Vol. 203. no. 4385, pp. 1122 - 1123
DOI: 10.1126/science.203.4385.1122
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Articles

Chemical Characterization of a Hormone That Promotes Cell Arrest in G2 in Complex Tissues

LANCE S. EVANS 1, MARIA S. ALMEIDA 1, DAVID G. LYNN 1, and KOJI NAKANISHI 2

1 Laboratory of Plant Morphogenesis, Manhattan College, Bronx, New York 10471
2 Department of Chemistry, Columbia University, New York 10027

A G2|factor in the cotyledons of Pisum sativum, which arrests the growth of cells in both roots and shoots in the G2 stage of the cell cycle, has been isolated and identified as trigonelline (N-methylnicotinic acid). To our knowledge, trigonelline is the first hormone that effects cell arrest in complex tissues of plants and animals to be chemically identified.

Submitted on July 7, 1978
Revised on October 6, 1978


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds.
X.-q. Zheng, E. Hayashibe, and H. Ashihara (2005)
J. Exp. Bot. 56, 1615-1623
   Abstract »    Full Text »    PDF »
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P. V. Minorsky (2002)
Plant Physiology 128, 7-8
   Full Text »    PDF »


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