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Science 9 February 1979:
Vol. 203. no. 4380, pp. 554 - 556
DOI: 10.1126/science.760204
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Articles

Science, Vol 203, Issue 4380, 554-556
Copyright © 1979 by American Association for the Advancement of Science

articles

A regulatory locus for mouse beta-glucuronidase induction, Gur, controls messenger RNA activity

K Paigen, C Labarca, and G Watson

A regulatory locus in a higher organism has been shown to control a specific messenger RNA activity. The Gur locus in mice regulates the production of kidney beta-glucuronidase messenger RNA activity after induction of the beta-glucuronidase structural gene, Gus, by testosterone. beta-Glucuronidase messenger RNA was assayed by its ability to direct the synthesis of catalytically active murine beta-glucuronidase in Xenopus oocytes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Testosterone: a major determinant of extragenital sexual dimorphism.
C. Bardin and J. Catterall (1981)
Science 211, 1285-1294
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