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Science 9 February 1979:
Vol. 203. no. 4380, pp. 553 - 554
DOI: 10.1126/science.32621

Articles

Science, Vol 203, Issue 4380, 553-554
Copyright © 1979 by American Association for the Advancement of Science


articles

Fertilization: a uterine glycosaminoglycan stimulates the conversion of sperm proacrosin to acrosin

TJ Wincek, RF Parrish, and KL Polakoski

Acrosin is a proteinase required for mammalian fertilization, and in freshly ejaculated spermatozoa exists as an inactive zymogen, proacrosin. A factor prsent in uterine flushings of gilts stimulates the conversion of highly pruified boar proacrosin to acrosin. Characterization of this factor indicates that its active component is a glycosaminoglycan.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Semen-Coagulating Protein, SVS2, in Mouse Seminal Plasma Controls Sperm Fertility.
N. Kawano and M. Yoshida (2007)
Biol Reprod 76, 353-361
   Abstract »    Full Text »    PDF »
A Basic 18-Amino Acid Peptide Contains the Polysulfate-Binding Domain Responsible for Activation of the Boar Proacrosin/Acrosin System.
R.D. Moreno and C. Barros (2000)
Biol Reprod 62, 1536-1542
   Abstract »    Full Text »



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