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Science 22 December 1978:
Vol. 202. no. 4374, pp. 1289 - 1290
DOI: 10.1126/science.725605
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Articles

Science, Vol 202, Issue 4374, 1289-1290
Copyright © 1978 by American Association for the Advancement of Science

articles

Human leukocyte interferon purified to homogeneity

M Rubinstein, S Rubinstein, PC Familletti, MS Gross, RS Miller, AA Waldman, and S Pestka

One of the species of human interferon produced by incubation of leukocytes with Newcastle disease virus was purified to homogeneity. It exhibited one peak of activity coinciding with a single protein band on sodium dodecyl sulfate-polyacrylamide gel electrophoresis.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Interferons: 50 Years after Their Discovery, There Is Much More to Learn.
S. Pestka (2007)
J. Biol. Chem. 282, 20047-20051
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Molecular weight of human gamma interferon is similar to that of other human interferons.
Y. Yip, B. Barrowclough, C Urban, and J Vilcek (1982)
Science 215, 411-413
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Leukocyte Interferon-Induced Tumor Regression in Human Metastatic Breast Cancer, Multiple Myeloma, and Malignant Lymphoma.
J. U. GUTTERMAN, G. R. BLUMENSCHEIN, R. ALEXANIAN, H.-Y. YAP, A. U. BUZDAR, F. CABANILLAS, G. N. HORTOBAGYI, E. M. HERSH, S. L. RASMUSSEN, M. HARMON, et al. (1980)
Ann Intern Med 93, 399-406
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