Science 10 November 1978: Vol. 202. no. 4368, pp. 631 - 633 DOI: 10.1126/science.100883

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Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling: DOES THE Ca2+/NFAT SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?.

S. P. Armstrong, C. J. Caunt, R. C. Fowkes, K. Tsaneva-Atanasova, and C. A. McArdle (2009)
J. Biol. Chem. 284, 35746-35757
 |  Abstract »  |  Full Text »  |  PDF »

Kisspeptin Signaling in the Brain.

A. E. Oakley, D. K. Clifton, and R. A. Steiner (2009)
Endocr. Rev. 30, 713-743
 |  Abstract »  |  Full Text »  |  PDF »

GABAergic Transmission to Gonadotropin-Releasing Hormone (GnRH) Neurons Is Regulated by GnRH in a Concentration-Dependent Manner Engaging Multiple Signaling Pathways.

P. Chen and S. M. Moenter (2009)
J. Neurosci. 29, 9809-9818
 |  Abstract »  |  Full Text »  |  PDF »

Atrazine Inhibits Pulsatile Luteinizing Hormone Release Without Altering Pituitary Sensitivity to a Gonadotropin-Releasing Hormone Receptor Agonist in Female Wistar Rats.

C. D. Foradori, L. R. Hinds, W. H. Hanneman, M. E. Legare, C. M. Clay, and R. J. Handa (2009)
Biol Reprod 81, 40-45
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Gonadotropins and Estradiol in Premenopausal Women by Oral Administration of the Nonpeptide Gonadotropin-Releasing Hormone Antagonist Elagolix.

R. S. Struthers, A. J. Nicholls, J. Grundy, T. Chen, R. Jimenez, S. S. C. Yen, and H. P. Bozigian (2009)
J. Clin. Endocrinol. Metab. 94, 545-551
 |  Abstract »  |  Full Text »  |  PDF »

Proteasome Regulation of Dynamic Transcription Factor Occupancy on the GnRH-Stimulated Luteinizing Hormone {beta}-Subunit Promoter.

H. E. Walsh and M. A. Shupnik (2009)
Mol. Endocrinol. 23, 237-250
 |  Abstract »  |  Full Text »  |  PDF »

Motivations and Methods for Analyzing Pulsatile Hormone Secretion.

J. D. Veldhuis, D. M. Keenan, and S. M. Pincus (2008)
Endocr. Rev. 29, 823-864
 |  Abstract »  |  Full Text »  |  PDF »

Disease-causing Mutation in GPR54 Reveals the Importance of the Second Intracellular Loop for Class A G-protein-coupled Receptor Function.

J. L. Wacker, D. B. Feller, X.-B. Tang, M. C. DeFino, Y. Namkung, J. S. Lyssand, A. J. Mhyre, X. Tan, J. B. Jensen, and C. Hague (2008)
J. Biol. Chem. 283, 31068-31078
 |  Abstract »  |  Full Text »  |  PDF »

Kisspeptin and KISS1R: a critical pathway in the reproductive system.

E. Gianetti and S. Seminara (2008)
Reproduction 136, 295-301
 |  Abstract »  |  Full Text »  |  PDF »

The Relative Role of Gonadal Sex Steroids and Gonadotropin-Releasing Hormone Pulse Frequency in the Regulation of Follicle-Stimulating Hormone Secretion in Men.

N. Pitteloud, A. A. Dwyer, S. DeCruz, H. Lee, P. A. Boepple, W. F. Crowley Jr., and F. J. Hayes (2008)
J. Clin. Endocrinol. Metab. 93, 2686-2692
 |  Abstract »  |  Full Text »  |  PDF »

Advances in Male Contraception.

S. T. Page, J. K. Amory, and W. J. Bremner (2008)
Endocr. Rev. 29, 465-493
 |  Abstract »  |  Full Text »  |  PDF »

Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.

J. Roa, E. Vigo, D. Garcia-Galiano, J. M. Castellano, V. M. Navarro, R. Pineda, C. Dieguez, E. Aguilar, L. Pinilla, and M. Tena-Sempere (2008)
Am J Physiol Endocrinol Metab 294, E1088-E1096
 |  Abstract »  |  Full Text »  |  PDF »

Gonadotropin-Releasing Hormone-1 Neuronal Activity Is Independent of Cyclic Nucleotide-Gated Channels.

S. Constantin and S. Wray (2008)
Endocrinology 149, 279-290
 |  Abstract »  |  Full Text »  |  PDF »

Proteasome-Dependent Down-Regulation of Activated Nuclear Hippocampal Glucocorticoid Receptors Determines Dynamic Responses to Corticosterone.

B. L. Conway-Campbell, M. A. McKenna, C. C. Wiles, H. C. Atkinson, E. R. de Kloet, and S. L. Lightman (2007)
Endocrinology 148, 5470-5477
 |  Abstract »  |  Full Text »  |  PDF »

G Protein-Coupled Receptor Trafficking in Health and Disease: Lessons Learned to Prepare for Therapeutic Mutant Rescue in Vivo.

P. M. Conn, A. Ulloa-Aguirre, J. Ito, and J. A. Janovick (2007)
Pharmacol. Rev. 59, 225-250
 |  Abstract »  |  Full Text »  |  PDF »

Anterior Pituitary Leptin Expression Changes in Different Reproductive States: In Vitro Stimulation by Gonadotropin-releasing Hormone.

N. Akhter, B. W. Johnson, C. Crane, M. Iruthayanathan, Y.-H. Zhou, A. Kudo, and G. V. Childs (2007)
J. Histochem. Cytochem. 55, 151-166
 |  Abstract »  |  Full Text »  |  PDF »

Use of a vascular access port for the measurement of pulsatile luteinizing hormone in old broiler breeders..

C. Senthilkumaran, S. Peterson, M. Taylor, and G. Bedecarrats (2006)
Poult. Sci. 85, 1632-1640
 |  Abstract »  |  Full Text »  |  PDF »

GPR54 and kisspeptin in reproduction.

M. Tena-Sempere (2006)
Hum. Reprod. Update 12, 631-639
 |  Abstract »  |  Full Text »  |  PDF »

Identification of new gonadotrophin-releasing hormone partial agonists..

A. Leanos-Miranda, A. Ulloa-Aguirre, L. A Cervini, J. A. Janovick, J. Rivier, and P M. Conn (2006)
J. Endocrinol. 189, 509-517
 |  Abstract »  |  Full Text »  |  PDF »

An Ensemble Model of the Male Gonadal Axis: Illustrative Application in Aging Men.

D. M. Keenan, P. Y. Takahashi, P. Y. Liu, P. D. Roebuck, A. X. Nehra, A. Iranmanesh, and J. D. Veldhuis (2006)
Endocrinology 147, 2817-2828
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Single or Repeated Intravenous Administration of Kisspeptin upon Dynamic LH Secretion in Conscious Male Rats.

S. Tovar, M. J. Vazquez, V. M. Navarro, R. Fernandez-Fernandez, J. M. Castellano, E. Vigo, J. Roa, F. F. Casanueva, E. Aguilar, L. Pinilla, et al. (2006)
Endocrinology 147, 2696-2704
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms for Pulsatile Regulation of the Gonadotropin Subunit Genes by GNRH1.

H. A. Ferris and M. A. Shupnik (2006)
Biol Reprod 74, 993-998
 |  Abstract »  |  Full Text »  |  PDF »

Continuous Human Metastin 45-54 Infusion Desensitizes G Protein-Coupled Receptor 54-Induced Gonadotropin-Releasing Hormone Release Monitored Indirectly in the Juvenile Male Rhesus Monkey (Macaca mulatta): A Finding with Therapeutic Implications.

S. B. Seminara, M. J. DiPietro, S. Ramaswamy, W. F. Crowley Jr., and T. M. Plant (2006)
Endocrinology 147, 2122-2126
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Steroid Milieu on Gonadotropin-Releasing Hormone-1 Neuron Firing Pattern and Luteinizing Hormone Levels in Male Mice.

J. Pielecka and S. M. Moenter (2006)
Biol Reprod 74, 931-937
 |  Abstract »  |  Full Text »  |  PDF »

Gonadotropin-Releasing Hormone Pulse Frequency-Dependent Activation of Extracellular Signal-Regulated Kinase Pathways in Perifused L{beta}T2 Cells.

H. Kanasaki, G. Y. Bedecarrats, K.-Y. Kam, S. Xu, and U. B. Kaiser (2005)
Endocrinology 146, 5503-5513
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Endogenous Activation of Metabotropic Glutamate Receptors Modulates GABAergic Transmission to Gonadotropin-Releasing Hormone Neurons and Alters Their Firing Rate: A Possible Local Feedback Circuit.

Z. Chu and S. M. Moenter (2005)
J. Neurosci. 25, 5740-5749
 |  Abstract »  |  Full Text »  |  PDF »

The Evolution of in Vitro Fertilization: Integration of Pharmacology, Technology, and Clinical Care.

E. C. Feinberg, J. G. Bromer, and W. H. Catherino (2005)
J. Pharmacol. Exp. Ther. 313, 935-942
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Biology of Gonadotropin-Releasing Hormone (GnRH)-I, GnRH-II, and Their Receptors in Humans.

C. K. Cheng and P. C. K. Leung (2005)
Endocr. Rev. 26, 283-306
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Duodenum and Macronutrient Type in Ghrelin Regulation.

J. Overduin, R. S. Frayo, H. J. Grill, J. M. Kaplan, and D. E. Cummings (2005)
Endocrinology 146, 845-850
 |  Abstract »  |  Full Text »  |  PDF »

GABAergic Integration of Progesterone and Androgen Feedback to Gonadotropin-Releasing Hormone Neurons.

S. D. Sullivan and S. M. Moenter (2005)
Biol Reprod 72, 33-41
 |  Abstract »  |  Full Text »  |  PDF »

Prolactin Mediates Photoperiodic Immune Enhancement: Effects of Administration of Exogenous Prolactin on Circulating Concentrations, Receptor Expression, and Immune Function in Steers.

T.L. Auchtung and G.E. Dahl (2004)
Biol Reprod 71, 1913-1918
 |  Abstract »  |  Full Text »  |  PDF »

Menopausal Increases in Pulsatile Gonadotropin-Releasing Hormone Release in a Nonhuman Primate (Macaca mulatta).

A. C. Gore, B. M. Windsor-Engnell, and E. Terasawa (2004)
Endocrinology 145, 4653-4659
 |  Abstract »  |  Full Text »  |  PDF »

Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution.

D. E. Cummings, J. Overduin, and K. E. Foster-Schubert (2004)
J. Clin. Endocrinol. Metab. 89, 2608-2615
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Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: Implications for a common fertility disorder.

S. D. Sullivan and S. M. Moenter (2004)
PNAS 101, 7129-7134
 |  Abstract »  |  Full Text »  |  PDF »

Effect of long-term treatment with low doses of the LHRH antagonist Cetrorelix on pituitary receptors for LHRH and gonadal axis in male and female rats.

J. E. Horvath, G. L. Toller, A. V. Schally, A.-M. Bajo, and K. Groot (2004)
PNAS 101, 4996-5001
 |  Abstract »  |  Full Text »  |  PDF »

Relationship of Endogenous Sex Hormones to Coronary Heart Disease: A Twin Study.

K. H. Mikulec, L. Holloway, R. E. Krasnow, H. Javitz, G. E. Swan, T. Reed, R. Marcus, and D. Carmelli (2004)
J. Clin. Endocrinol. Metab. 89, 1240-1245
 |  Abstract »  |  Full Text »  |  PDF »

Misrouted cell surface GnRH receptors as a disease aetiology for congenital isolated hypogonadotrophic hypogonadism.

A. Ulloa-Aguirre, J. A. Janovick, A. Leanos-Miranda, and P. M. Conn (2004)
Hum. Reprod. Update 10, 177-192
 |  Abstract »  |  Full Text »  |  PDF »

{gamma}-Aminobutyric Acid Neurons Integrate and Rapidly Transmit Permissive and Inhibitory Metabolic Cues to Gonadotropin-Releasing Hormone Neurons.

S. D. Sullivan and S. M. Moenter (2004)
Endocrinology 145, 1194-1202
 |  Abstract »  |  Full Text »  |  PDF »

Dose-Dependent Switch in Response of Gonadotropin-Releasing Hormone (GnRH) Neurons to GnRH Mediated through the Type I GnRH Receptor.

C. Xu, X.-Z. Xu, C. S. Nunemaker, and S. M. Moenter (2004)
Endocrinology 145, 728-735
 |  Abstract »  |  Full Text »  |  PDF »

Neurobiological mechanisms of puberty in higher primates.

T. M. Plant and M. L. Barker-Gibb (2004)
Hum. Reprod. Update 10, 67-77
 |  Abstract »  |  Full Text »  |  PDF »

Proteasomal Degradation of Runx2 Shortens Parathyroid Hormone-induced Anti-apoptotic Signaling in Osteoblasts: A PUTATIVE EXPLANATION FOR WHY INTERMITTENT ADMINISTRATION IS NEEDED FOR BONE ANABOLISM.

T. Bellido, A. A. Ali, L. I. Plotkin, Q. Fu, I. Gubrij, P. K. Roberson, R. S. Weinstein, C. A. O'Brien, S. C. Manolagas, and R. L. Jilka (2003)
J. Biol. Chem. 278, 50259-50272
 |  Abstract »  |  Full Text »  |  PDF »

Neurosteroids Alter {gamma}-Aminobutyric Acid Postsynaptic Currents in Gonadotropin-Releasing Hormone Neurons: A Possible Mechanism for Direct Steroidal Control.

S. D. Sullivan and S. M. Moenter (2003)
Endocrinology 144, 4366-4375
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Hypothalamic-Pituitary-Gonadal Axis in Estrogen Receptor (ER) Null Mice Reveals Hypergonadism and Endocrine Sex Reversal in Females Lacking ER{alpha} But Not ER{beta}.

J. F. Couse, M. M. Yates, V. R. Walker, and K. S. Korach (2003)
Mol. Endocrinol. 17, 1039-1053
 |  Abstract »  |  Full Text »  |  PDF »

Relative Effect of Gonadotropin-Releasing Hormone (GnRH)-I and GnRH-II on Gonadotropin Release.

V. S. Densmore and H. F. Urbanski (2003)
J. Clin. Endocrinol. Metab. 88, 2126-2134
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Gonadotropin Subunit Gene Promoter Activity by Pulsatile Gonadotropin-Releasing Hormone (GnRH) in Perifused L{beta}T2 Cells: Role of GnRH Receptor Concentration.

G. Y. Bedecarrats and U. B. Kaiser (2003)
Endocrinology 144, 1802-1811
 |  Abstract »  |  Full Text »  |  PDF »

Roles for Ghrelin in the Regulation of Appetite and Body Weight.

D. E. Cummings and M. H. Shannon (2003)
Arch Surg 138, 389-396
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Is Treatment with a Luteinizing Hormone-Releasing Hormone Agonist Justified in Short Adolescents?.

M. M. Lee (2003)
N. Engl. J. Med. 348, 942-945
 |  Full Text »  |  PDF »

Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats.

J. E. Horvath, A. M. Bajo, A. V. Schally, M. Kovacs, F. Herbert, and K. Groot (2002)
PNAS 99, 15048-15053
 |  Abstract »  |  Full Text »  |  PDF »

In Situ GABAergic Modulation of Synchronous Gonadotropin Releasing Hormone-1 Neuronal Activity.

J. P. Moore Jr, E. Shang, and S. Wray (2002)
J. Neurosci. 22, 8932-8941
 |  Abstract »  |  Full Text »  |  PDF »

Pituitary responsiveness to GnRH in mares following deslorelin acetate implantation to hasten ovulation.

C. A. Johnson, D. L. Thompson Jr., and J. A. Cartmill (2002)
J Anim Sci 80, 2681-2687
 |  Abstract »  |  Full Text »  |  PDF »

Predictors of Outcome of Long-Term GnRH Therapy in Men with Idiopathic Hypogonadotropic Hypogonadism.

N. Pitteloud, F. J. Hayes, A. Dwyer, P. A. Boepple, H. Lee, and W. F. Crowley Jr. (2002)
J. Clin. Endocrinol. Metab. 87, 4128-4136
 |  Abstract »  |  Full Text »  |  PDF »

Prenatal LHRH Neurons in Nasal Explant Cultures Express Estrogen Receptor {beta} Transcript.

N. Sharifi, A. E. Reuss, and S. Wray (2002)
Endocrinology 143, 2503-2507
 |  Abstract »  |  Full Text »  |  PDF »

Estradiol-Sensitive Afferents Modulate Long-Term Episodic Firing Patterns of GnRH Neurons.

C. S. Nunemaker, R. A. DeFazio, and S. M. Moenter (2002)
Endocrinology 143, 2284-2292
 |  Abstract »  |  Full Text »  |  PDF »

Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery.

D. E. Cummings, D. S. Weigle, R. S. Frayo, P. A. Breen, M. K. Ma, E. P. Dellinger, and J. Q. Purnell (2002)
N. Engl. J. Med. 346, 1623-1630
 |  Abstract »  |  Full Text »  |  PDF »

Sexual hormone abnormalities in male patients with renal failure.

A. Schmidt, A. Luger, and W. H. Horl (2002)
Nephrol. Dial. Transplant. 17, 368-371
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Disruption of the hypothalamic luteinizing hormone pulsing mechanism in aging men.

D. M. Keenan and J. D. Veldhuis (2001)
Am J Physiol Regulatory Integrative Comp Physiol 281, R1917-R1924
 |  Abstract »  |  Full Text »  |  PDF »

Chronic (60-Week) Toxicity Study of DUROS Leuprolide Implants in Dogs.

M. J. Cukierski, P. A. Johnson, and J. C. Beck (2001)
International Journal of Toxicology 20, 369-381
 |  Abstract »  |  PDF »

Long-Term Recordings of Networks of Immortalized GnRH Neurons Reveal Episodic Patterns of Electrical Activity.

C. S. Nunemaker, R. A. DeFazio, M. E. Geusz, E. D. Herzog, G. R. Pitts, and S. M. Moenter (2001)
J Neurophysiol 86, 86-93
 |  Abstract »  |  Full Text »  |  PDF »

The Fertile Eunuch Variant of Idiopathic Hypogonadotropic Hypogonadism: Spontaneous Reversal Associated with a Homozygous Mutation in the Gonadotropin-Releasing Hormone Receptor.

N. Pitteloud, P. A. Boepple, S. DeCruz, S. B. Valkenburgh, W. F. Crowley Jr., and F. J. Hayes (2001)
J. Clin. Endocrinol. Metab. 86, 2470-2475
 |  Abstract »  |  Full Text »  |  PDF »

Perspective: The Importance of Genetic Defects in Humans in Elucidating the Complexities of the Hypothalamic-Pituitary-Gonadal Axis.

S. B. Seminara and W. F. Crowley Jr. (2001)
Endocrinology 142, 2173-2177
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Cycles of Transcription and Translation Do Not Comprise the Gonadotropin-Releasing Hormone Pulse Generator in GT1 Cells.

G. R. Pitts, C. S. Nunemaker, and S. M. Moenter (2001)
Endocrinology 142, 1858-1864
 |  Abstract »  |  Full Text »

Luteinizing Hormone-Releasing Hormone (LHRH) Biosynthesis and Secretion in Embryonic LHRH Neurons.

J. P. Moore Jr. and S. Wray (2000)
Endocrinology 141, 4486-4495
 |  Abstract »  |  Full Text »  |  PDF »

Alteration in the Hypothalamic-Pituitary-Ovarian Axis in Depressed Women.

E. A. Young, A. R. Midgley, N. E. Carlson, and M. B. Brown (2000)
Arch Gen Psychiatry 57, 1157-1162
 |  Abstract »  |  Full Text »  |  PDF »

Whole-Cell Recordings from Preoptic/Hypothalamic Slices Reveal Burst Firing in Gonadotropin-Releasing Hormone Neurons Identified with Green Fluorescent Protein in Transgenic Mice.

K. J. Suter, J.-P. Wuarin, B. N. Smith, F. E. Dudek, and S. M. Moenter (2000)
Endocrinology 141, 3731-3736
 |  Abstract »  |  Full Text »  |  PDF »

Decrease in Gonadotropin-Releasing Hormone (GnRH) Pulse Frequency with Aging in Postmenopausal Women.

J. E. Hall, H. B. Lavoie, E. E. Marsh, and K. A. Martin (2000)
J. Clin. Endocrinol. Metab. 85, 1794-1800
 |  Abstract »  |  Full Text »

Divergent and Composite Gonadotropin-Releasing Hormone-Responsive Elements in the Rat Luteinizing Hormone Subunit Genes.

J. Weck, A. C. Anderson, S. Jenkins, P. C. Fallest, and M. A. Shupnik (2000)
Mol. Endocrinol. 14, 472-485
 |  Abstract »  |  Full Text »

Physiology of the Menstrual Cycle.

S D Silberstein and G R Merriam (2000)
Cephalalgia 20, 148-154
 |  Abstract »  |  Full Text »  |  PDF »

Hexapeptide and Cyclic Pentapeptide Endothelin Antagonists Directly Activate Pituitary Gonadotropin-Releasing Hormone Receptors.

D. Yahalom, Y. Koch, N. Ben-Aroya, and M. Fridkin (2000)
Mol. Pharmacol. 57, 718-724
 |  Abstract »  |  Full Text »

A Subset of Gonadotropin-Releasing Hormone Neurons in the Ovine Medial Basal Hypothalamus Is Activated during Increased Pulsatile Luteinizing Hormone Secretion.

R. Boukhliq, R. L. Goodman, S. J. Berriman, B. Adrian, and M. N. Lehman (1999)
Endocrinology 140, 5929-5936
 |  Abstract »  |  Full Text »

Gender-Specific Exacerbation of Murine Lupus by Gonadotropin-Releasing Hormone: Potential Role of G{alpha}q/11.

J. D. Jacobson, M. A. Ansari, M. Kinealy, and V. Muthukrishnan (1999)
Endocrinology 140, 3429-3437
 |  Abstract »  |  Full Text »

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?.

J. F. Couse and K. S. Korach (1999)
Endocr. Rev. 20, 358-417
 |  Abstract »  |  Full Text »

The Reproductive Endocrine Associates of the Massachusetts General Hospital: Fifteen Years of Integrated Clinical Practice and Investigation.

S. B. Seminara, J. E. Hall, A. E. Taylor, W. F. Crowley Jr., and K. A. Martin (1999)
J. Clin. Endocrinol. Metab. 84, 1912-1918
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Free {alpha}-Subunit Is Superior to Luteinizing Hormone as a Marker of Gonadotropin-Releasing Hormone Despite Desensitization at Fast Pulse Frequencies.

F. J. Hayes, D. J. McNicholl, D. Schoenfeld, E. E. Marsh, and J. E. Hall (1999)
J. Clin. Endocrinol. Metab. 84, 1028-1036
 |  Abstract »  |  Full Text »

Gonadotropin-Releasing Hormone Regulation of Gonadotropin Subunit Gene Expression in Female Rats: Actions on Follicle-Stimulating Hormone {beta} Messenger Ribonucleic Acid (mRNA) Involve Differential Expression of Pituitary Activin ({beta}-B) and Follistatin mRNAs.

A. C. Dalkin, D. J. Haisenleder, J. T. Gilrain, K. Aylor, M. Yasin, and J. C. Marshall (1999)
Endocrinology 140, 903-908
 |  Abstract »  |  Full Text »

Cocaine Impairs Follicular Phase Pulsatile Gonadotropin Secretion in Rhesus Monkeys.

E. C. Chen, M. H. Samuels, M. F. Luther, T. S. King, C. A. Eddy, T. M. Siler-Khodr, and R. S. Schenken (1998)
Reproductive Sciences 5, 311-316
 |  Abstract »  |  PDF »

Gonadotropin-Releasing Hormone Deficiency in the Human (Idiopathic Hypogonadotropic Hypogonadism and Kallmann's Syndrome): Pathophysiological and Genetic Considerations.

S. B. Seminara, F. J. Hayes, and W. F. Crowley Jr. (1998)
Endocr. Rev. 19, 521-539
 |  Abstract »  |  Full Text »

Gonadotropin-Releasing Hormone Pulses Are Required to Maintain Activation of Mitogen-Activated Protein Kinase: Role in Stimulation of Gonadotrope Gene Expression.

D. J. Haisenleder, M. E. Cox, S. J. Parsons, and J. C. Marshall (1998)
Endocrinology 139, 3104-3111
 |  Abstract »  |  Full Text »  |  PDF »

Potential Regulatory Roles for G Protein-Coupled Receptor Kinases and {beta}-Arrestins in Gonadotropin-Releasing Hormone Receptor Signaling.

J. D. Neill, L. W. Duck, L. C. Musgrove, and J. C. Sellers (1998)
Endocrinology 139, 1781-1788
 |  Abstract »  |  Full Text »  |  PDF »

Differential Use of Signal Transduction Pathways in the Gonadotropin-Releasing Hormone-Mediated Regulation of Gonadotropin Subunit Gene Expression.

B. D. Saunders, E. Sabbagh, W. W. Chin, and U. B. Kaiser (1998)
Endocrinology 139, 1835-1843
 |  Abstract »  |  Full Text »  |  PDF »

Differential Gonadotropin-Releasing Hormone Stimulation of Rat Luteinizing Hormone Subunit Gene Transcription by Calcium Influx and Mitogen-Activated Protein Kinase-Signaling Pathways.

J. Weck, P. C. Fallest, L. K. Pitt, and M. A. Shupnik (1998)
Mol. Endocrinol. 12, 451-457
 |  Abstract »  |  Full Text »

Diurnal and Ultradian Rhythmicity of Plasma Leptin: Effects of Gender and Adiposity.

M. F. Saad, M. G. Riad-Gabriel, A. Khan, A. Sharma, R. Michael, S. D. Jinagouda, R. Boyadjian, and G. M. Steil (1998)
J. Clin. Endocrinol. Metab. 83, 453-459
 |  Abstract »  |  Full Text »

Increased Levels and Pulsatility of Follicle-Stimulating Hormone in Mothers of Hereditary Dizygotic Twins.

C. B. Lambalk, D. I. Boomsma, L. de Boer, C. H. de Koning, E. Schoute, C. Popp-Snijders, and J. Schoemaker (1998)
J. Clin. Endocrinol. Metab. 83, 481-486
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Luteinizing Hormone-Releasing Hormone (LHRH) Neurons Maintained in Hypothalamic Slice Explant Cultures Exhibit a Rapid LHRH mRNA Turnover Rate.

J. A. Maurer and S. Wray (1997)
J. Neurosci. 17, 9481-9491
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Differential Activation of Protein Kinase C delta  and epsilon  Gene Expression by Gonadotropin-releasing Hormone in alpha T3-1 Cells. AUTOREGULATION BY PROTEIN KINASE C.

D. Harris, N. Reiss, and Z. Naor (1997)
J. Biol. Chem. 272, 13534-13540
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Expression of Ryanodine Receptors in the Pituitary Gland: Evidence for a Role in Gonadotropin-Releasing Hormone Signaling.

S. Sundaresan, J. Weiss, A. C. Bauer-Dantoin, and J. L. Jameson (1997)
Endocrinology 138, 2056-2065
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Differential Effects of Gonadotropin-Releasing Hormone (GnRH) Pulse Frequency on Gonadotropin Subunit and GnRH Receptor Messenger Ribonucleic Acid Levels in Vitro.

U. B. Kaiser, A. Jakubowiak, A. Steinberger, and W. W. Chin (1997)
Endocrinology 138, 1224-1231
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Studies of Gonadotropin-Releasing Hormone (GnRH) Action Using GnRH Receptor-Expressing Pituitary Cell Lines.

U. B. Kaiser, P. M. Conn, and W. W. Chin (1997)
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Laboratory Monitoring of Children With Precocious Puberty.

P. A. Lee (1994)
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The regulation of chemotaxis and chemokinesis in Dictyostelium amoebae by temporal signals and spatial gradients of cyclic AMP.

M. Vicker (1994)
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Advances in the Management of Precocious Puberty.

P. A. Lee (1994)
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Growth-Hormone-Releasing Hormone: A Clinical Update.

M. L. VANCE and M. O. THORNER (1986)
Ann Intern Med 105, 447-449
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Use of Gonadotropic Hormones and Sex Steroids in Assessing Male Reproduction.

R. J. Witorsch (1986)
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Luteinizing Hormone Releasing Hormone Analogue Therapy for Central Precocious Puberty: Long-term Effect on Somatic Growth, Bone Maturation, and Predicted Height.

F. Comite, F. Cassorla, K. M. Barnes, K. D. Hench, A. Dwyer, M. C. Skerda, D. L. Loriaux, G. B. Cutler Jr, and O. H. Pescovitz (1986)
JAMA 255, 2613-2616
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Therapeutic Applications of Luteinizing-Hormone-Releasing Hormone and Its Analogs.

G. B. CUTLER Jr., A. R. HOFFMAN, R. S. SWERDLOFF, R. J. SANTEN, D. R. MELDRUM, and F. COMITE (1985)
Ann Intern Med 102, 643-657
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Clomiphene-Responsive Hypogonadism in Sickle Cell Anemia.

C. S. LANDEFELD, M. SCHAMBELAN, S. L. KAPLAN, and S. H. EMBURY (1983)
Ann Intern Med 99, 480-483
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Anterior Pituitary Hormone Secretion in Chronic Schizophrenics: Responses to Administration of Hypothalamic Releasing Hormones.

I. N. Ferrier, E. C. Johnstone, T. J. Crow, and I. Rincon-Rodriguez (1983)
Arch Gen Psychiatry 40, 755-761
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Neuroendocrinology and Impotence.

R. F. SPARK (1983)
Ann Intern Med 98, 103-105
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Hepatic glucose production oscillates in synchrony with the islet secretory cycle in fasting rhesus monkeys.

C. Goodner, F. Hom, and D. Koerker (1982)
Science 215, 1257-1260
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Extrapituitary action of gonadotropin-releasing hormone: direct inhibition ovarian steroidogenesis.

A. Hsueh and G. Erickson (1979)
Science 204, 854-855
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Rapid Down-regulation of the Type I Inositol 1,4,5-Trisphosphate Receptor and Desensitization of Gonadotropin-releasing Hormone-mediated Ca2+ Responses in alpha T3-1 Gonadotropes.

G. B. Willars, J. E. Royall, S. R. Nahorski, F. El-Gehani, H. Everest, and C. A. McArdle (2001)
J. Biol. Chem. 276, 3123-3129
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