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Science 1 September 1978:
Vol. 201. no. 4358, pp. 824 - 826
DOI: 10.1126/science.210502
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Articles

Science, Vol 201, Issue 4358, 824-826
Copyright © 1978 by American Association for the Advancement of Science

articles

Growth inhibition of transformed cells with succinylated concanavalin A

RJ Mannino, K Ballmer, and MM Burger

Succinylated concanavalin A reversibly inhibits the growth of SV40 transformed mouse 3T3 cells and thus causes an accumulation of the cells in the G1 phase of the cell cycle. In a soft substrate (methylcellulose) succinylated concanavalin A also restores in transformed cells the growth behavior typical of untransformed cells.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)