Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 28 July 1978:
Vol. 201. no. 4353, pp. 356 - 358
DOI: 10.1126/science.78523
Prev | Table of Contents | Next

Articles

Science, Vol 201, Issue 4353, 356-358
Copyright © 1978 by American Association for the Advancement of Science

articles

Estrogenic activity of the insecticide kepone on the chicken oviduct

RD Palmiter and ER Mulvihill

Kepone induces ovalbumin and conalbumin synthesis in explants of chick oviduct in vitro by acting as a weak estrogen. It binds to the nuclear estrogen receptor and is antagonized by the antiestrogen tamoxifen. Kepone also induces egg white protein synthesis in vivo by direct interaction with estrogen receptors and by indirectly increasing the concentration of progesterone in the serum.




To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)