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Science 14 July 1978:
Vol. 201. no. 4351, pp. 176 - 178
DOI: 10.1126/science.663649
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Articles

Science, Vol 201, Issue 4351, 176-178
Copyright © 1978 by American Association for the Advancement of Science

articles

Sympathetic nervous control of cerebrospinal fluid production from the choroid plexus

M Lindvall, L Edvinsson, and C Owman

The rabbit choroid plexus, responsible for the bulk production of cerebrospinal fluid, is well supplied by sympathetic nerves emanating in the superior cervical ganglia. Electrical stimulation of these nerves markedly reduces production of cerebrospinal fluid, measured by [14C] inulin dilution during ventricular perfusion, whereas sympathetic denervation enhances the rate of formation.


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