Science, Vol 200, Issue 4348, 1390-1392
Copyright © 1978 by American Association for the Advancement of Science
Identification of a C-glucuronide of delta6- tetrahydrocannabinol as a mouse liver conjugate in vivo
S Levy,
B Yagen,
and
R Mechoulam
Delta 6-Tetrahydrocannabinol-C-4-glucuronide was found in the livers of mice that had been administered delta 6-tetrahydrocannabinol. Thus, C-glucuronidation of a compound that contains a free hydroxyl group has been demonstrated in vivo.