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Science 9 June 1978:
Vol. 200. no. 4346, pp. 1175 - 1177
DOI: 10.1126/science.653362
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Articles

Science, Vol 200, Issue 4346, 1175-1177
Copyright © 1978 by American Association for the Advancement of Science

articles

Striatal nondopaminergic neurons: possible involvement in feeding and drinking behavior

DJ Pettibone, N Kaufman, MC Scally, E Meyer Jr, I Ulus, and LD Lytle

Intracaudate injections of kainic acid destroy striatal neurons containing acetylcholine and gamma-aminobutyric acid but leave dopaminergic nerve terminals in this brain region intact. Rats injected with the drug are aphagic and adipsic, and have other behavioral abnormalities strikingly similar to those seen in animals with lesions in the dopaminergic nigrostriatal bundle.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)